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COVID-19 Check-in 2.0

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Comments

  • Tdub0199Tdub0199 Posts: 1,977 ✭✭✭✭✭ Graduate
  • YaleDawgYaleDawg Posts: 7,163 ✭✭✭✭✭ Graduate

    If it is working the way you claim where the proportion of positives is the same but more are asymptomatic within the HCQ group, you would expect there to be a higher proportion of symptomatic people in the control group. That was not the case in this trial.

  • YaleDawgYaleDawg Posts: 7,163 ✭✭✭✭✭ Graduate
    edited July 2020

    So if your spouse had a PCR confirmed case of COVID-19, and you started developing COVID-19 symptoms you wouldn't think you had COVID-19?

  • YaleDawgYaleDawg Posts: 7,163 ✭✭✭✭✭ Graduate

    I wouldn't put much stock into this group. First, this was a video put together by breitbart and the America's frontline doctors group does not disclose who owns or funds the group, but it is known they work directly with the Tea party patriots. Of the doctors listed in their group none of them are infectious disease experts.

  • PerroGrandePerroGrande Posts: 6,185 ✭✭✭✭✭ Graduate
    edited July 2020

    @texdawg I wanted to make a couple of points on something you brought up, even though I can't find it anymore. This is getting very little discussion in the media, but it is absolutely huge imho: the three biggest hotspots right now are TX, FL and CA. All three have or will soon pass NY in total cases. Also, those three states have the most seniors (65+). In fact, those three states have right at 25% of all the seniors in the US--one in four in just three states, about 13 million people! The one thing most everyone agrees on is that age is probably the biggest risk factor for mortality in CV 19. So, we should see a higher death rate in these states. We don't. All #s rounded and from Worldometer.

    Cases Deaths

    CA 467K 8.55K

    FL 442 6.12K

    TX 404K 5.88K

    NY 441K 32.7K

    NY has around a third of the cases of the big three combined, yet it has over 50% more deaths! And consider that there are over 4X more seniors in those states. They are more at risk. Not only that, but if you add the cases from the big five in Europe--Spain, UK, Italy, Germany, and France, you get a number very close to our big three. Europe ~1.26MM cases; TX/FL/CA 1.31MM cases. Yet, Europe's big 5, even though they have slightly less cases, have lost just under 150,000 souls to CV 19--more than 7X our big three with higher cases. Perhaps the deadliest place on earth for cases to fatalities is Connecticut, where just under 10% of the positives died. You can see that our big three are currently at about 1.5%, or one sixth of CT's rate. Now, many of the cases are active in the big three, so the numbers will likely get worse, but they shouldn't get anywhere close to NY or CT or Europe in rates. There could be a number of explanations, but I think it is fair to say the disease is much less deadly in summer.

  • Casanova_FlatulenceCasanova_Flatulence Posts: 3,126 ✭✭✭✭✭ Graduate

    That's what I thought, an unsubstantiated political ad hominem that demonstrates a confirmed case of TDS.

  • PerroGrandePerroGrande Posts: 6,185 ✭✭✭✭✭ Graduate

    How do you know any of the numbers are correct if you don't actually test the people? Better question, why even publish something like this without accurate data?

  • YaleDawgYaleDawg Posts: 7,163 ✭✭✭✭✭ Graduate

    How is it not accurate? They looked at high risk exposures and found that giving HCQ had no effect on the development of COVID-19 symptoms. Do you think they are lying about people developing symptoms?

  • texdawgtexdawg Posts: 11,581 ✭✭✭✭✭ Graduate
  • PerroGrandePerroGrande Posts: 6,185 ✭✭✭✭✭ Graduate
    edited July 2020

    Because they didn't test either group to see if they actually had CV. They looked at symptoms. I can't tell you how many people I know who were sure they had the disease, only to test negative. Seriously, Yale, you are smarter than this. If we were going to test a drug, wouldn't we have to use a validated test to determine whether the disease was present? How much more with Covid! This disease can mimic half of the diseases in the textbook.

  • YaleDawgYaleDawg Posts: 7,163 ✭✭✭✭✭ Graduate
    edited July 2020

    "Four infectious disease physicians who were unaware of the trial-group assignments reviewed symptomatic participants to generate a consensus with respect to whether their condition met the case definition."

    The study was rigorous and carried out very well. It doesn't fit your bias so you make up reasons to malign it.

  • PerroGrandePerroGrande Posts: 6,185 ✭✭✭✭✭ Graduate

    I could seriously care less on HCQ. I do wish we could find something that worked, but it is all empirical to me. I will objectively consider both sides. I don't see anything that works great--remdesivir, HCQ, nothing appears to be a knockout punch. Four physicians reviewing symptoms is wholly inadequate. The results are worthless because they didn't actually test the people to see whether they had the disease. Remarkable because the technology is there to do it. This one won't age well imho. I'm shocked that you would defend the results. When you say RCTs prove this or that, I will have to discount it because you are defending this study instead of criticizing it.

  • YaleDawgYaleDawg Posts: 7,163 ✭✭✭✭✭ Graduate

    just take the L man. It seems you just want to take the opposite stance of everything I say because I won't go along with vitamin D cures everything stance you hold dear. The study was carried out well and the four physicians who specialize in infectious disease are definitely enough. In the absence of testing what else could you want? Yeah, PCR testing is best, but the authors went to great lengths in its absence. I agree remdesivir is definitely not a panacea. It has some marginal benefits, but is by no means a wonder drug.

    Ah there it is with that last line. You desperately want me to be wrong about this so you can hold it up as an example when I criticize vit D studies. Sad.

  • SupraSupra Posts: 109 ✭✭✭ Junior

    Fwiw I haven't read the study, but it's possible that the purpose wasn't to prevent infection.

    Could have been a trial to prevent the development of severe and life threatening symptoms, which would then make sense to have clinicians grade the symptoms.

This discussion has been closed.